Anesthesiology:

No abstract available

CONCLUSIONS: These findings highlight unique compositional and functional changes in the gut microbiome of individuals with CRPS, thus contributing to the growing body of evidence supporting the role of the gut microbiome in chronic pain syndromes. Furthermore, they pave the way for further studies elucidating the pathophysiology of CRPS and exploring new diagnostic aids and treatment modalities.

CONCLUSIONS: Prophylactic dexamethasone during adult cardiac surgery was associated with reduced composite clinical outcomes, renal failure, and shorter hospital stays, and seemed associated with 30-day mortality in patients >80 years old.

CONCLUSIONS: These findings identify key psychological and coping correlates of mental defeat in persons with CNCP on LTOT, informing the development of interventions to mitigate it, and thereby reducing the risk of suicide in this vulnerable population.

PURPOSE: Provision of anesthesia care must go hand in hand with surgical care to equitably widen surgical coverage of underserved populations, especially the rural segments of low- and middle-income countries. The aim of this study was to assess the availability of key items and infrastructure needed for anesthesia care.

OBJECTIVES: High-impact chronic pain (HICP), affecting 36.4% of individuals with chronic pain, significantly limits work, social, and self-care activities. Effective treatments for HICP remain elusive. In addition to pain catastrophizing, growing evidence suggests that pain self-efficacy may be a treatment target for HICP. Our study examines the relative contributions of pain self-efficacy and catastrophizing to health outcomes in patients with HICP.

CONCLUSIONS: Older patients with preoperative cognitive impairment undergoing general anesthesia have higher mortality and morbidity rates, particularly in patients with KDSQ-C scores ≥11.

BACKGROUND: There are significant racial and ethnic differences in healthcare outcomes, including pain treatment.

INTRODUCTION: Tonsillectomy, a common childhood surgery, is associated with difficult postoperative recovery. Previous reviews provided low-grade evidence that honey may improve recovery. The BEE PAIN FREE study investigated whether honey alongside multimodal analgesia improved the recovery trajectory in children following tonsillectomy.

This educational article discusses the current understanding of the pericaspular nerve group block (PENG) of the hip regarding its mechanism of action and spread patterns, as well as plausible explanations for postblock quadriceps weakness. Finally, we will discuss the recent evidence of PENG block as an analgesic block in hip fractures and in different hip surgeries.

No abstract available

No abstract available

CONCLUSIONS: The combination of dexmedetomidine and lidocaine laryngopharynx spray effectively suppresses the cough reflex during extubation, reduces postoperative sore throat, and stabilizes hemodynamics in female patients undergoing thyroid surgery.

CONCLUSIONS: These findings suggest that HIFU may be more effective than RFA in inducing thermal necrosis of the nerve.

CONCLUSIONS: Despite the initial reduction in the incidence of IOCA, this study highlights a temporal increase coinciding with the COVID-19 pandemic and an increase in nonelective surgeries. Future research should explore more granular predictors of IOCA and its outcomes to develop targeted interventions for at-risk populations and tailor guidelines to manage emerging challenges in population health.

CONCLUSIONS: SGB appears to be a safe and effective treatment that may provide temporary stabilization between the onset of ES and catheter ablation, while also aiding in the management of persistent ES post-catheter ablation and newly developed ES following cardiac surgery.

CONCLUSIONS: Our preliminary study demonstrates the potential feasibility and safety of real-time monitoring of LA diffusion in rabbits using the novel perfluoropropane UCA under 2D ultrasound.

Pain experiences in adolescence are increasing and represent a major public health concern. However, little is known about the neurobiological phenotype of pain experiences in adolescents, particularly outside of a clinical setting. A better neurobiological understanding of pain experiences in community youth may shed light on potential vulnerabilities present before clinical diagnoses of chronic pain. This study utilized an exploratory region-of-interest approach, in a large community sample (n = 7332) of youth (ages 11-12), to examine the association between white matter microstructure, fractional anisotropy (FA) and mean diffusivity (MD), and pain experiences. Bayesian multilevel modeling was used to explore group differences (between those reporting past-month pain and those who did not), and continuous associations between pain experiences (average pain intensity, worst pain intensity, and pain-related limitations) and FA and MD. Sex differences in these effects were also explored. Analyses revealed widespread associations between pain-related limitations and lower FA and greater MD in male but not female youth. Furthermore, average pain intensity was associated with greater superior corticostriate and superior longitudinal fasciculus MD in all youth, and worst pain intensity was associated with lower inferior fronto-occipital fasciculus FA in male youth. There were no group differences in FA or MD between those with or without past-month pain. These findings suggest that white matter microstructural alterations in youth may be more related to the severity of the pain experience than to the presence or absence of pain itself, with male youth showing stronger neurobiological associations with pain-related outcomes.

CONCLUSIONS: These results validate the antinociceptive power of CeAGA neurons using a different approach. Additionally, we highlight distinct roles of CeAGA neurons in governing physiological pain, acute pain, and the transition to chronic pain through KCC2 dysregulation.

CONCLUSIONS: GLP-1 agonist therapy was associated with higher residual gastric volumes and higher risks of full stomachs in fasted diabetic patients. GLP-1 agonist use within 7 days of surgery was also associated with higher gastric volumes relative to holding therapy for over 7 days, supporting current consensus-based guidelines.