Seminars in thrombosis and hemostasisJournal Article
02 May 2025
Catheter-related thrombosis (CRT) poses serious risks for cancer patients. Identifying risk factors and implementing targeted interventions can prevent CRT. To explore thromboelastogram parameters and clinical risk factors for CRT in elderly lung cancer patients. A total of 663 elderly lung cancer patients were selected from three hospitals in Hunan, Hainan, and Qinghai provinces in China from January 1, 2022, to June 30, 2024. The patients were divided into two groups: a CRT group (221 patients) and a non-CRT group (442 patients), with a ratio of 1:2. A between-group comparison and binary logistic regression were used to analyze risk factors for CRT in elderly lung cancer patients. Binary logistic regression analysis showed that decreased (odds ratio [OR]: 0.849, 95% confidence interval [CI]: 0.763-0.945, = 0.003), decreased (0.571, 95% CI: 0.404-0.807, = 0.001), advanced age (OR: 1.073, 95% CI: 1.033-1.113, < 0.001), elevated platelet count (OR: 1.006, 95% CI: 1.004-1.009, < 0.001), increased hemoglobin level (OR: 1.020, 95% CI: 1.009-1.031, < 0.001), shortened PT (OR: 0.904, 95% CI: 0.830-0.985, = 0.022), surgery ≤ 1 month (OR: 2.258, 95% CI: 1.420-3.590, = 0.001), male sex (OR: 4.534, 95% CI: 2.815-7.304, < 0.001), diabetes (OR: 2.478, 95% CI: 1.373-4.472, = 0.003), hypertension (OR: 2.386, 95% CI: 1.505-3.784, < 0.001), physical activity disorders (OR: 9.038, 95% CI: 4.462-18.309, < 0.001) were independent risk factors for CRT in elderly lung cancer patients. Independent risk factors for CRT in elderly lung cancer patients include decreased -values and decreased -values, shortened PT, advanced age, elevated platelet count, increased hemoglobin level, surgery ≤ 1 month, male sex, diabetes, hypertension, and physical activity disorders.
None declared.
More resources:
Share: