Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma.

Abstract

UpdateOf

bioRxiv. 2023 May 03:2023.05.02.538892. doi: 10.1101/2023.05.02.538892.

COI Statement

K. Sikkink reports personal fees from Arima Genomics outside the submitted work. C.P. Fulco reports a patent for “CRISPR methods and enhancer mapping” (US20200143907A1) pending and is employed by and may hold stock in Sanofi. A.D. Schmitt reports other support from University of Michigan during the conduct of the study and other support from Arima Genomics outside the submitted work; in addition, A.D. Schmitt has a patent for WO2020106776A2 pending and issued. J.M. Engreitz reports grants from the NIH during the conduct of the study and nonfinancial support from 10x Genomics, personal fees from GSK plc, and personal fees from Roche Genentech outside the submitted work; in addition, J.M. Engreitz has a patent for U.S. Patent App. 16/337,846 issued, licensed, and with royalties paid from related to CRISPR technologies used in this work. R.J.H. Ryan reports grants from the NIH/NCI, V Foundation for Cancer Research, and American Society of Hematology and nonfinancial support from Arima Genomics and BioNano Genomics during the conduct of the study, as well as grants from the Hyundai Hope On Wheels Foundation outside the submitted work. No disclosures were reported by the other authors.

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